III. Innovative concepts for target-identification, diagnosis and therapy
In recent years modern bioscience has yielded powerful techniques for the qualitative and quantitative analysis of complex biological processes (e.g., "omics" technologies). Such global approaches yield large data sets, which can no longer be evaluated intuitively and require computer-assisted evaluation tools. Projects in category III will foster interdisciplinary synergies with computer sciences and other modern approaches to develop new concepts for target-identification, diagnosis or therapy.
Project 3-1
Prof. Dr. Kirsten Bacia (MLU Chemistry)
- Development of a platform for analyzing interactions of target proteins in isolated native membranes
Project 3-2
Prof. Dr. Sven-Erik Behrens (MLU Biochemistry and Biotechnology)
PD Dr. Selma Gago-Zachert (Leibniz Institute of Plant Biochemistry)
Project 3-3
Prof. Dr. Dariush Hinderberger (MLU Chemistry)
- Characterization of effects of buffer and salt-ions on the molecular and macroscopic behaviour of highly-concentrated solutions of therapeutic monoclonal antibodies (mAb)
Project 3-4
Prof. Dr. Patrick Michl (MLU Medicine)
- p90-RSK as a synthetic-lethal target for pancreatic carcinoma – molecular characterization and therapeutic inhibition
Project 3-5
Prof. Dr. Klaus Pillen (MLU Agricultural and Nutritional Sciences)
Prof. Dr. Björn Junker (MLU Pharmacy)
- Genomic prediction: Prediction of flowering time and yield by analyzing SNPs and metabolites in the barley population HEB-25 to expedite breeding
Project 3-6
Prof. Dr. Milton Stubbs (MLU Biochemistry and Biotechnology)